Sodium Hypochlorite in Endodontics
Disinfection And Obturation
Sodium Hypochlorite in Endodontics:
Contributed By: Dr.Mayur P. Kankar
It’s an EXCELLENT non-specific PROTEOLYTIC and ANTIMICROBIAL agent.
It is the MOST COMMON irrigation solution used during root canal therapy.
Mechanism of action Sodium hypochlorite exhibits a dynamic balance
as shown by the following reaction:
NaOCl + H2O ↔ NaOH + HOCl ↔ Na+ + OH- + H+ + OCl
• Sodium hypochlorite has a wide range activity against both GRAM POSITIVE and GRAM NEGATIVE BACTERIA
• Sodium hypochlorite is the STRONGEST ANTIFUNGAL agent among root canal irrigations and medications
• Sodium hypochlorite is the only root canal irrigant that can destroy the microbial biofilm effectively
• Utilizing sodium hypochlorite for decontamination of the microbial sampling field is controversial
• It seems that dentine reduces or inhibits the antibacterial activity of sodium hypochlorite
• Sodium hypochlorite is a non-specific proteolytic agent with an EXECELLENT TISSUE DISSOLVING ability
• Effects of sodium hypochlorite on the mechanical properties and the cutting efficiency of Nickel-Titanium instruments are still controversial
• It seems that HEATING sodium hypochlorite INCREASES its antimicrobial and tissue dissolving abilities
• Sodium hypochlorite exerts deteriorative effects on mechanical properties and chemical composition of dentine
• Effects of sodium hypochlorite on the bond strength of bonding systems are still controversial
• EXCELLENT HAEMOSTATIC ACTIVITY of sodium hypochlorite may enhance the prognosis of vital pulp therapy
• Cytotoxicity and tissue toxicity of sodium hypochlorite is well documented & most complications of the use of sodium hypochlorite appear to be the result of its inadvertent injection beyond the root apex which can cause violent tissue reactions(hypochlorite accident) , In rare cases sodium hypochlorite may cause allergic reaction.
[Ref.International journal 2008 (58)]