Sodium Hypochlorite in Endodontics
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Sodium Hypochlorite in Endodontics

Disinfection And Obturation

Endodontics

Sodium Hypochlorite in Endodontics:

Contributed By: Dr.Mayur P. Kankar

It’s an EXCELLENT non-specific PROTEOLYTIC and ANTIMICROBIAL agent.

It is the MOST COMMON irrigation solution used during root canal therapy.

Mechanism of action Sodium hypochlorite exhibits a dynamic balance

as shown by the following reaction:

NaOCl + H2O ↔ NaOH + HOCl ↔ Na+ + OH- + H+ + OCl

• Sodium hypochlorite has a wide range activity against both GRAM POSITIVE and GRAM NEGATIVE BACTERIA

• Sodium hypochlorite is the STRONGEST ANTIFUNGAL agent among root canal irrigations and medications

• Sodium hypochlorite is the only root canal irrigant that can destroy the microbial biofilm effectively

• Utilizing sodium hypochlorite for decontamination of the microbial sampling field is controversial

• It seems that dentine reduces or inhibits the antibacterial activity of sodium hypochlorite

• Sodium hypochlorite is a non-specific proteolytic agent with an EXECELLENT TISSUE DISSOLVING ability

• Effects of sodium hypochlorite on the mechanical properties and the cutting efficiency of Nickel-Titanium instruments are still controversial

• It seems that HEATING sodium hypochlorite INCREASES its antimicrobial and tissue dissolving abilities

• Sodium hypochlorite exerts deteriorative effects on mechanical properties and chemical composition of dentine

• Effects of sodium hypochlorite on the bond strength of bonding systems are still controversial

EXCELLENT HAEMOSTATIC ACTIVITY of sodium hypochlorite may enhance the prognosis of vital pulp therapy

• Cytotoxicity and tissue toxicity of sodium hypochlorite is well documented & most complications of the use of sodium hypochlorite appear to be the result of its inadvertent injection beyond the root apex which can cause violent tissue reactions(hypochlorite accident) , In rare cases sodium hypochlorite may cause allergic reaction.

[Ref.International journal 2008 (58)]

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